一种新型依匹斯汀鼻腔给药制剂及其制备方法

Novel epinastine nasal drug delivery preparation and preparation method thereof

Abstract

The invention provides a novel epinastine nasal drug delivery preparation and a preparation method thereof. According to the requirements of nose drops and biological characteristics of epinastine, an appropriate protective agent, a thickener and a corrosion remover are added to prepare aqueous solution nose drops. The novel epinastine nasal drug delivery preparation is free of bitter taste and thrill, and is suitable for nasal delivery, convenient to use, and especially suitable for medication on children and the old. The technological process provided by the invention has the advantages of being simple and reliable, and good in repeatability, can be applied to prevention and treatment of anaphylactic (including seasonal or non-seasonal) rhinitis, and has certain application value in clinical.
本发明提供了一种新型依匹斯汀鼻腔给药制剂及其制备方法,根据滴鼻剂的要求及依匹斯汀生物学特性,加入适当的保护剂、增稠剂、防腐剂制成水溶液滴鼻剂,无苦味和刺激性,适用于鼻腔给药,使用方便,尤其适用于儿童及老人用药,本发明提供的工艺过程,具有简便可靠,重现性良好的优点,可用于过敏性(包括季节性或非季节性)鼻炎的预防和治疗,在临床上具有一定的应用价值。

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    Publication numberPublication dateAssigneeTitle
    CN-104817467-AAugust 05, 2015北京桑普生物化学技术有限公司Composition capable of enhancing stability of sodium hydroxymethyl glycinate solution and screening method